Anti-inflammatory Activity of Essential Oil of Canarium Strictum Roxb

Authors

  • Ragunathan Muthuswamy Department of Pharmacognosy, Nehru College of Pharmacy, Pampady, Thiruvilwamala, Thrissur District, Kerala–680 597, India
  • Senthamarai R Periyar College of Pharmaceutical Sciences, Periyar Centenary Educational Complex, K. Sathanoor Main Road, Tiruchirappalli-620021, Tamilnadu, India
Abstract:

Canarium L. is used in folk medicine as anti-inflammatory, antibacterial, antifungal, antitumor, heptoprotective, antioxidant, and anti diabetic properties. The present study investigeated the invivo anti-inflammatory activity of  essential oil obtained by hydrodistillation of resin of Canarium strictum Roxb. In the current study, anti-inflammatory activity of essential oil of Canarium strictum Roxb (10-100 mg/kg) has been established by using the carrageenan (acute inflammation model) and formalin (chronic inflammation model) induced paw edema in mice. The dose dependent activity has been observed, the higher dose 100 mg /kg (p<0.01) exhibited momentous anti-inflammatory activity that was compared with standard drug diclofenac sodium in both acute and chronic inflammatory animal models. The perceived anti-inflammatory activity might be due to inhibition of histamine, serotonin, kinins, substance P, prostaglandins, and bradykinin at the inflammed area. More elaborate investigation is needed to correlate the possible effect of major terpenes on inflammation. Our data recommend that EOCS inhibits the paw edema and granulation tissue in experimental animal models of chronic inflammation, and acute inflammation would be a probable choice for treatment of chronic and acute inflammatory disorders.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

anti-inflammatory activity of essential oil of canarium strictum roxb

canarium l. is used in folk medicine as anti-inflammatory, antibacterial, antifungal, antitumor, heptoprotective, antioxidant, and anti diabetic properties. the present study investigeated the invivo anti-inflammatory activity of  essential oil obtained by hydrodistillation of resin of canarium strictum roxb. in the current study, anti-inflammatory activity of essential oil of canarium strictum...

full text

Anti-inflammatory activity and chemical composition of Pycnocycla bashagardiana fruit’s essential oil in animal models

Objective(s): Pycnocycla bashagardiana is an endemic species found only in Iran. Due to the presence of myristicin as the major component of the fruit’s oil we were prompted to assess the antinociceptive and anti-inflammatory properties of P. bashagardiana fruit’s essential oil (PBFEO). Materials and Methods: The analgesic activities of PBFEO (100, 200, and 400 mg/kg, IP) were studied by hot-pl...

full text

Anti-Inflammatory Activity of Cymbopogon schoenanthus Essential Oil in Animal Models

Background and objectives: The species of Cymbopogon are generally used as anti-bacterial, anti-fungal, anti-malarial, and anti-spasmodic agents, as well as in cold treatment.Due to the presence of piperitone in Cymbopogon schoenanthus, we were prompted to evaluate were prompted to assess the anti-nociceptive and anti-inflammatory properties of its essential O...

full text

Evaluation of chemical composition, anti-inflammatory and anti-nociceptive effects of Eugenia caryophyllata buds essential oil

Background & Aim: Eugenia caryophyllata well known as Clove is a tree from Myrtaceae family that several parts of this plant traditionally used in dental care as an analgesic. This study aimed to assess the chemical composition, anti-inflammatory and anti-nociceptive activities of the essential oil extracted from Clove buds. Experimental: The essential oil of Clove buds (EOC) was extr...

full text

Evaluation of chemical composition, anti-inflammatory and anti-nociceptive effects of Eugenia caryophyllata buds essential oil

Background & Aim: Eugenia caryophyllata well known as Clove is a tree from Myrtaceae family that several parts of this plant traditionally used in dental care as an analgesic. This study aimed to assess the chemical composition, anti-inflammatory and anti-nociceptive activities of the essential oil extracted from Clove buds. Experimental: The essential oil of Clove buds (EOC) was extr...

full text

Anti-Inflammatory activity of Erythrina stricta Roxb. in Albino Rats

Objectives: To study the anti-inflammatory activity of Erythrina stricta extract in albino rats. Methods: Leaves of Erythrina stricta (ES) were extracted and subjected to Pharmacological studies. The Extract was screened for anti-inflammatory activity in albino rats using acute carrageenan paw oedema, formalin induced paw oedema and sub acute granuloma pouch model. Results: In acute phase infla...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 9  issue 2

pages  13- 21

publication date 2013-05-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023